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KMID : 1013220070050010021
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Jouranl of the Korean Society of Clinical Toxicology
2007 Volume.5 No. 1 p.21 ~ p.26
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Organophosphate-Pyrethroid Mixtures Poisoning
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Hong Dae-Young
Eo Eun-Kyung
Oh Bum-Jin
Lee Mi-Jin
Lee Sung-Woo
Kim Jun-Sig
Baek Kwang-Je
Lee Kyeong-Ryong
Park Joon-Seok
Kwon Woon-Yong
Seo Joo-Hyun
Roh Hyung-Keun
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Abstract
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Purpose: Owing to organophosphate-pyrethroid mixtures are widely used, suicidal or unintentional poisoning is common. But there have been relatively few reports of poisoning. The purpose of this study is to evaluate the difference of the severity and toxicity between organophosphate-pyrethroid mixtures poisoning and single organophosphate poisoning.
Methods: From August 2005 to July 2006, 65 patients presented with organophosphate-pyrethroid mixtures poisoning to emergency medical center. Date were gathered by report form it was drawn up.
Results: 65 patients were enrolled in 28 hospitals and their mean age was years old. The most common cause of poisoning was suicide, in 52 cases(80%). Chlorpyrifos-cypermethrin, malathion-esfenvalerate were the most frequent chemicals involved, and the mean ingestion amount was 135.4ml. The most common symptom of the patients was nausea/vomiting, in 16 patients. The average GCS score was 13. The mean ICU stay was days, and mortality was 3.1%.
Conclusion: The severity and toxicity of organophosphate-pyrethroid mixture poisoning were lower than that of single organophosphate poisoning.
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KEYWORD
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Organophosphates, Pyrethroids, Poisoning
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